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reabsorption is also associated with another class of collecting duct cells, the intercalated cells (see Figure 9 3)4 The principal cells reabsorb sodium; the luminal entry step is via epithelial sodium channels Regulation of this entry step is enormously important for wholebody physiology, and we expand on this topic in 7 Some sodium chloride reabsorption continues in the medullary collecting ducts, probably via some form of epithelial sodium channels What about water reabsorption in tubular segments beyond the loop of Henle The water permeability of the distal convoluted tubule is always very low and unchanging, similar to that of the ascending limbs of Henle s loop Accordingly, as fluid flows through the distal convoluted tubule and sodium chloride reabsorption proceeds, virtually no water is reabsorbed The result is that the already hypo-osmotic fluid entering the distal convoluted tubule from the thick ascending limb of Henle s loop becomes even more hypo-osmotic Thus, the distal convoluted tubule, like the ascending limbs of Henle s loop, functions as a diluting segment and further separates salt from water In contrast, the water permeability of the collecting-duct system both the cortical and medullary portions is subject to physiological control by circulating antidiuretic hormone (ADH; see Figure 6 5) The inner medullary collecting duct has at least a finite water permeability even in the absence of ADH, but the outer medullary and cortical regions have a vanishingly low water permeability without ADH Depending on levels of ADH, therefore, water permeability for most of the collecting-duct system can be very low, very high, or everything in between When water permeability is very low, the hypo-osmotic fluid entering the collecting-duct system from the distal convoluted tubule remains hypo-osmotic as it flows along the ducts When this fluid reaches the medullary portion of the collecting ducts, there is now a huge osmotic gradient favoring reabsorption, which occurs to some extent That is, although there is little cortical water reabsorption without ADH (where most distal absorption normally occurs), there is still a finite medullary absorption because of the enormous osmotic gradient However, because there is such a high tubular volume (ie, it was not reabsorbed in the cortex), most of the water entering the medullary collecting duct flows on to the ureter The result is the excretion of a large volume of very hypoosmotic (dilute) urine, or water diuresis In water diuresis, the last tubular segment to reabsorb large amounts of water is the descending limb of Henle s loop; in all later segments reabsorption of solute (mainly sodium chloride) continues, but water reabsorption is minimal (although not zero in the inner medulla) Note that even when very little water reabsorption occurs beyond the loop of Henle, the reabsorption of sodium is not retarded to any great extent Therefore, the intraluminal sodium concentration can be lowered almost to zero in these tubular segments, and the osmolality can approach. data matrix excel 2013 Data Matrix Excel Barcode Generator - Free download and software ...
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QR Code | Data Matrix | PDF417 for Excel - Generate QR-Code, Data Matrix, Aztec and PDF417 2D barcode symbols directly in Microsoft Excel spreadsheets. 5 Once the shortcut is created, right-click on it to select Properties 6 On the General tab, click the Advanced button 7 In the Advanced dialog box, select Run with different credentials Click OK to close the dialog box 8 Click OK to close the Properties dialog box The shortcut is ready Now you can move it to the Quick Launch Area When you use the shortcut, it automatically displays the Run As dialog box You can then choose to run it with your current credentials or select The following user and enter administrative credentials (see Figure 1-1) Alternatively, you can create Run As shortcuts through the command line Simply put it in a text file with the cmd extension and point the shortcut to this file The command line gives you the opportunity to refine the use of the Run As command through switches that alter its default behavior In addition, the command line lets you create a single cmd file that includes start commands for all of the tools you use to perform regular administrative Figure 5.9 Building a professionallooking interface for custom Editor Parts enhances the user experience. 2d data matrix excel Data Matrix Excel Barcode Generator - Free download and software ...
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